aecopd的兩種治療方法藥物經(jīng)濟學(xué)的研究.doc
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aecopd的兩種治療方法藥物經(jīng)濟學(xué)的研究,aecopd的兩種治療方法藥物經(jīng)濟學(xué)的研究摘要:目的 研究兩種治療方法治療慢性阻塞性肺疾病伴急性加重期(aecopd)的藥物經(jīng)濟學(xué)效果。方法 采用回顧性研究方法,將102例aecopd患者按照治療方法中使用的抗菌藥物不同分為美洛西林舒巴坦鈉組(a組)和頭孢米諾鈉組(b組),住院天數(shù)為7~14天,分別觀察2組治療后的療效...
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AECOPD的兩種治療方法藥物經(jīng)濟學(xué)的研究
摘要:目的 研究兩種治療方法治療慢性阻塞性肺疾病伴急性加重期(AECOPD)的藥物經(jīng)濟學(xué)效果。方法 采用回顧性研究方法,將102例AECOPD患者按照治療方法中使用的抗菌藥物不同分為美洛西林舒巴坦鈉組(A組)和頭孢米諾鈉組(B組),住院天數(shù)為7~14天,分別觀察2組治療后的療效和不良反應(yīng)發(fā)生率并以其評估治療的效果,然后運用藥物經(jīng)濟學(xué)評價方法中的成本-效果分析方法、敏感度分析方法及DDDs進行分析。結(jié)果 A組和B組臨床總有效率分別為93.55%、95.00%(P>0.05),不良反應(yīng)發(fā)生率分別為3.23%、2.50%;平均住院時間分別為(9.19±2.17)天和(8.90±1.98)天,譆@殺痙直鷂�(7695.18±2993.02)元、(9648.49±2631.41)元,統(tǒng)計學(xué)分析兩組有顯著性差異(P0.05)。結(jié)論 治療AECOPD,美洛西林舒巴坦鈉治療方法較頭孢米諾鈉治療方法經(jīng)濟、有效、合理。
關(guān)鍵詞:慢性阻塞性肺疾病伴急性加重期;治療方法;成本-效果分析;敏感度分析;
DDDs
Abstract: Objective To research chronic obstructive pulmonary disease with acute exacerbation ( AECOPD) of two antibaccterial drug treatments of pharmacoeconomic effect. Methods by a retrospective exploration, so medical records were divided into Mezlocillin sodium/Sulbactam sodium (A)group and Cefninox sodium (B)group as different treatment methods, the length of hospital stay was 7~14 days, then observed 2 groups of adverse reaction and curative effect after treatment, and eva luated the effect of treatment with those, the last cost-effectiveness analysis(CEA),sensitivity analysis and frequency of medication DDDs were performed. Results The clinical total effective rates in group A and group B were 93.55% and 95.00%,the incidence of adverse reaction were 3.23%, 2.50%,Mean length of hospital stay were (9.19±2.17)days and (8.90±1.98)days, and the total costs were (7695.18±2993.02) Yuan and (9648.49±2631.41)Yuan, statistical analysis of the two groups had significant difference (P<0.05);The cost-effectiveness ratio of Mezlocillin sodium/Sulbactam sodium (A)group is lower than that of Cefninox (B)group, the sensitivity analysis results are consistent with results of parameter change.In addition, DDDsA
Keywords:AECOPD; Methods of treatment; Cost-effectiveness analysis ; Sensitivity analysis ;DDDs
摘要:目的 研究兩種治療方法治療慢性阻塞性肺疾病伴急性加重期(AECOPD)的藥物經(jīng)濟學(xué)效果。方法 采用回顧性研究方法,將102例AECOPD患者按照治療方法中使用的抗菌藥物不同分為美洛西林舒巴坦鈉組(A組)和頭孢米諾鈉組(B組),住院天數(shù)為7~14天,分別觀察2組治療后的療效和不良反應(yīng)發(fā)生率并以其評估治療的效果,然后運用藥物經(jīng)濟學(xué)評價方法中的成本-效果分析方法、敏感度分析方法及DDDs進行分析。結(jié)果 A組和B組臨床總有效率分別為93.55%、95.00%(P>0.05),不良反應(yīng)發(fā)生率分別為3.23%、2.50%;平均住院時間分別為(9.19±2.17)天和(8.90±1.98)天,譆@殺痙直鷂�(7695.18±2993.02)元、(9648.49±2631.41)元,統(tǒng)計學(xué)分析兩組有顯著性差異(P0.05)。結(jié)論 治療AECOPD,美洛西林舒巴坦鈉治療方法較頭孢米諾鈉治療方法經(jīng)濟、有效、合理。
關(guān)鍵詞:慢性阻塞性肺疾病伴急性加重期;治療方法;成本-效果分析;敏感度分析;
DDDs
Abstract: Objective To research chronic obstructive pulmonary disease with acute exacerbation ( AECOPD) of two antibaccterial drug treatments of pharmacoeconomic effect. Methods by a retrospective exploration, so medical records were divided into Mezlocillin sodium/Sulbactam sodium (A)group and Cefninox sodium (B)group as different treatment methods, the length of hospital stay was 7~14 days, then observed 2 groups of adverse reaction and curative effect after treatment, and eva luated the effect of treatment with those, the last cost-effectiveness analysis(CEA),sensitivity analysis and frequency of medication DDDs were performed. Results The clinical total effective rates in group A and group B were 93.55% and 95.00%,the incidence of adverse reaction were 3.23%, 2.50%,Mean length of hospital stay were (9.19±2.17)days and (8.90±1.98)days, and the total costs were (7695.18±2993.02) Yuan and (9648.49±2631.41)Yuan, statistical analysis of the two groups had significant difference (P<0.05);The cost-effectiveness ratio of Mezlocillin sodium/Sulbactam sodium (A)group is lower than that of Cefninox (B)group, the sensitivity analysis results are consistent with results of parameter change.In addition, DDDsA
Keywords:AECOPD; Methods of treatment; Cost-effectiveness analysis ; Sensitivity analysis ;DDDs