伴盆腔炎性疾病婦科圍手術期抗菌藥物使用與術后感染相關性研究

摘要：目的 調(diào)查所在醫(yī)院住院患者中伴盆腔炎性疾病婦科手術患者圍手術期抗菌藥物的使用現(xiàn)狀，分析抗菌藥物使用合理與否與術后感染的相關性以及分析術后感染的影響因素。方法 通過調(diào)查廈門市中醫(yī)院2012年伴盆腔炎性疾病的婦科手術患者抗菌藥物使用情況及術后感染情況，采用SPSS19.0軟件分析術后感染與抗菌藥物使用合理與否的相關性及其它影響因素。結果 1、抗菌藥物使用合理組（A組）56例，術后感染率5.36%，不合理組（B組）160例，術后感染率5.63%，兩組差異無統(tǒng)計學意義，但是前者術后感染率低于后者。2、術后感染率與年齡、術前是否存在感染灶、是否用藥、用藥時機、累計給藥時間、用藥品種數(shù)、年齡等自身因素和醫(yī)療因素與術后感染率存在相關性（r>0.3）。結論 伴盆腔炎性疾病的婦科手術患者，圍手術期抗菌藥物是否合理使用、術前預防感染時機、術后療程是否合理等醫(yī)療因素以及患者自身因素是患者術后感染與否的重要危險因素。所以，為降低患者術后感染率，提高患者生活質量，除患者應該提高對自身因素的認識外，醫(yī)院更應重視合理使用抗菌藥物，加強院感管理。

關鍵詞：盆腔炎性疾??；圍手術期；婦科；抗菌藥物使用；術后感染；相關性

Abstract: Objective To investigated hospital patients with pelvic inflammatory disease in female patients with gynecological operation during operation period of usage of antibiotic drugs in hospital, analyzed antimicrobial drug use was reasonable or not correlated with postoperative infection, then analyzed the influence factors of postoperative infection. Methods Through the investigation of Xiamen city Chinese medicine hospital in 2012 with pelvic inflammatory disease of the use of antibacterial agents in patients with gynecologic surgery and postoperative infection, the SPSS19.0 software was used to analysis the correlation between postoperative infection and antimicrobial drug use was reasonable analyzed other factors. Results The use of antibacterial drugs reasonably group (A group) had 56 cases, postoperative infection rate of it was 5.36%;the unreasonable group (B group) had 160 cases, postoperative infection rate of it was 5.63%, the two groups had no significant difference, but the postoperative infection rate was lower than the latter. There had Correlation between whether use the drug, when give the medication, course of the postoperative, number of drugs, ages or other factors and postoperative infection. Conclusion Gynecological operation in patients with pelvic inflammatory disease, whether the operation period of the rational use of antibiotics, preoperative infection time, postoperative treatment is reasonable medical factors as well as the patient's own factors are important risk factors in patients with postoperative or not. So, in order to reduce postoperative infection rate, improve the quality of life of patients, in addition to the patients should raise the awareness of their own factors, the hospital should pay more attention to the rational use of antimicrobial drugs, to strengthen hospital infection management.
Keywords: Pelvic inflammatory disease; perioperative period; Department of gynecology; Antimicrobial drug use; postoperative infection; correlation