病變二尖瓣的水利特性研究.doc
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病變二尖瓣的水利特性研究,1.48萬字自己原創(chuàng)的畢業(yè)論文，僅在本站獨家出售，重復(fù)率低，推薦下載使用摘要 二尖瓣是人體心臟的重要瓣膜組織，二尖瓣脫垂是指二尖瓣葉（前葉、后葉或兩葉）在心室收縮期脫入左心房（向左房側(cè)膨出），伴或不伴有二尖瓣關(guān)閉不全二尖瓣反流，會造成左心室擴張以及左心室功能障礙，一般而言約有10-20%的人有這...
內(nèi)容介紹
此文檔由會員 淘寶大夢 發(fā)布
病變二尖瓣的水利特性研究
1.48萬字
自己原創(chuàng)的畢業(yè)論文，僅在本站獨家出售，重復(fù)率低，推薦下載使用
摘要 二尖瓣是人體心臟的重要瓣膜組織，二尖瓣脫垂是指二尖瓣葉（前葉、后葉或兩葉）在心室收縮期脫入左心房（向左房側(cè)膨出），伴或不伴有二尖瓣關(guān)閉不全二尖瓣反流，會造成左心室擴張以及左心室功能障礙，一般而言約有10-20%的人有這種現(xiàn)象，但是絕大部分的人都無癥狀，本身并無太大的的研究意義與必要,而二尖瓣腱索斷裂幾乎總是導(dǎo)致急性、常常是嚴重的二尖瓣返流,或使慢性二尖瓣返流急性惡化.所以研究二尖瓣腱索斷裂的特性對于病態(tài)二尖瓣病因的檢測以及臨床修復(fù)手術(shù)具有十分重要的指導(dǎo)意義.而由于生理系統(tǒng)本身的復(fù)雜機制以及生物體檢測的困難我們不得不利用電路模擬仿真進行量化分析[1]。而傳統(tǒng)的電路模擬系統(tǒng)一般是用一個二極管串接一個線性或者非線性電阻這樣的簡單模型來模擬。這種方法主要是模擬血液的單向流動特性。但是卻忽略了諸如血液回流.瓣膜物理特征等重要特性。本文則采用的是實驗臺控制水壓模擬瓣膜兩端壓力變化進行水利實驗,從而得到相對準確的二尖瓣特性曲線。
本文首先介紹了實驗的一些背景資料如當前的研究成果以及對本次實驗的指導(dǎo)意義。而后對整個實驗的過程以及整個實驗裝置的調(diào)整進行了闡述和分析，對實驗結(jié)果也進行了初步的處理,隨后還將根據(jù)流體特性對結(jié)果進一步處理以得到更為準確的二尖瓣特性曲線。
本次實驗的主要工作意義在于利用水流模擬血液流動,并且利用真實豬心二尖瓣進行實驗,回避了電路模型對于瓣膜生物特性的仿真不完全,能夠更準確的測量出液體通過腱索斷裂二尖瓣時壓力流量的變化,對于二尖瓣乃至整個左心血液循環(huán)系統(tǒng)的仿真建模有著重要指導(dǎo)作用。
關(guān)鍵詞：病變二尖瓣 腱索斷裂 房室壓差 血液流量方向 二尖瓣的特性曲線
Study on Hydraulic characteristics of The Diseased Mitral
Abstract Mitral valve tissue is an important part of human heart , mitral valve prolapse is the mitral valve (anterior , posterior lobe or both lobes ) in ventricular systole off into the left atrium ( left atrial side bulging ) , with or without mitral regurgitation mitral regurgitation can cause left ventricular dilatation and left ventricular dysfunction , in general , about 10-20 % of people have this phenomenon, but most people are asymptomatic itself is not much research significance and necessary, and mitral valve chordae rupture almost always lead to acute , often severe mitral regurgitation , or to acute exacerbation of chronic mitral regurgitation , so research two mitral valve chordae rupture properties for the detection of pathological etiology and clinical mitral valve repair surgery has a very important significance . rather difficult due to the complex biological mechanisms and physiological detection system itself we had to use circuit simulation quantitative analysis . The traditional circuit simulation system is generally a diode in series with a linear or non-linear resistance of such a simple model to simulate . This method is to simulate the characteristics of one-way flow of blood . But it ignores the important features such as the backflow of blood . Valvular physical characteristics.
This paper adopts the bench hydraulic control valve simulation experiment ends of Water Conservancy pressure changes , resulting in relatively accurate mitral valve characteristic curve.This paper describes the experimental paper first introduces some background information such as the current research and guidance for this experiment . Then for several changes throughout the experiment and the adjustment of the entire experimental setup are described and analyzed , the experimental results have also been preliminary processing , fluid properties will then be further processed in accordance with the results to obtain more accurate mitral characteristic curve.
The main significance of this experiment is to use hydraulic simulation of blood flow , and use real pig heart mitral experiment avoided the circuit model for the biological characteristics of the valve ignored , can more accurately measure the liquid through the mitral chordae rupture changes in pressure and flow valve , the mitral valve for simulation modeling and the whole left heart circulatory system plays an important role in guiding .
Key words： Mitral valve disease Chordal rupture Atrioventricular pressure Blood flow direction Mitral valve characteristic curve
目 錄
第一章 緒論 1
1.1 二尖瓣腱索斷裂的研究歷史及發(fā)展現(xiàn)狀 1
1.1.1 二尖瓣腱索斷裂研究的發(fā)展狀況 1
1.1.2 心血管建模仿真技術(shù)的現(xiàn)況 1
1.2 課題研究的背景、主要內(nèi)容及意義 2
1.2.1 課題研究的背景 2
1.2.2 課題的主要研究內(nèi)容及意義 4
1.3 小結(jié) 4
第二章 經(jīng)由二尖瓣的血液循環(huán)原理結(jié)構(gòu) 5
2.1左心血液循環(huán)過程 5
2.2 二尖瓣的模型 6
2.3 模擬左心環(huán)境的實驗裝置整體設(shè)計 6
2.4 小結(jié) 7
第三章 實驗裝置設(shè)計及實驗流程 8
3.1 實驗總體設(shè)計 8
3.2靜態(tài)實驗裝置搭建 8
3.3動態(tài)實驗裝置搭建 12
第四章 實驗步驟 16
4.1實驗準備及注意事項 16
4.1.1二尖瓣數(shù)據(jù)記錄 16
4.1.2二尖瓣解剖流程 16
4.1.3 二尖瓣安裝步驟 17
4.2 靜態(tài)實驗 18
4.2.1 靜態(tài)正向?qū)嶒炦^程 18
4.2.2 靜態(tài)返流實驗過程 19
4.3動態(tài)實驗 20
4.4 小結(jié)和實驗結(jié)果預(yù)測 21
第五章 實驗結(jié)果及分析 22
5.1 實驗設(shè)計 22
5.2 系統(tǒng)測試調(diào)試 22-..
1.48萬字
自己原創(chuàng)的畢業(yè)論文，僅在本站獨家出售，重復(fù)率低，推薦下載使用
摘要 二尖瓣是人體心臟的重要瓣膜組織，二尖瓣脫垂是指二尖瓣葉（前葉、后葉或兩葉）在心室收縮期脫入左心房（向左房側(cè)膨出），伴或不伴有二尖瓣關(guān)閉不全二尖瓣反流，會造成左心室擴張以及左心室功能障礙，一般而言約有10-20%的人有這種現(xiàn)象，但是絕大部分的人都無癥狀，本身并無太大的的研究意義與必要,而二尖瓣腱索斷裂幾乎總是導(dǎo)致急性、常常是嚴重的二尖瓣返流,或使慢性二尖瓣返流急性惡化.所以研究二尖瓣腱索斷裂的特性對于病態(tài)二尖瓣病因的檢測以及臨床修復(fù)手術(shù)具有十分重要的指導(dǎo)意義.而由于生理系統(tǒng)本身的復(fù)雜機制以及生物體檢測的困難我們不得不利用電路模擬仿真進行量化分析[1]。而傳統(tǒng)的電路模擬系統(tǒng)一般是用一個二極管串接一個線性或者非線性電阻這樣的簡單模型來模擬。這種方法主要是模擬血液的單向流動特性。但是卻忽略了諸如血液回流.瓣膜物理特征等重要特性。本文則采用的是實驗臺控制水壓模擬瓣膜兩端壓力變化進行水利實驗,從而得到相對準確的二尖瓣特性曲線。
本文首先介紹了實驗的一些背景資料如當前的研究成果以及對本次實驗的指導(dǎo)意義。而后對整個實驗的過程以及整個實驗裝置的調(diào)整進行了闡述和分析，對實驗結(jié)果也進行了初步的處理,隨后還將根據(jù)流體特性對結(jié)果進一步處理以得到更為準確的二尖瓣特性曲線。
本次實驗的主要工作意義在于利用水流模擬血液流動,并且利用真實豬心二尖瓣進行實驗,回避了電路模型對于瓣膜生物特性的仿真不完全,能夠更準確的測量出液體通過腱索斷裂二尖瓣時壓力流量的變化,對于二尖瓣乃至整個左心血液循環(huán)系統(tǒng)的仿真建模有著重要指導(dǎo)作用。
關(guān)鍵詞：病變二尖瓣 腱索斷裂 房室壓差 血液流量方向 二尖瓣的特性曲線
Study on Hydraulic characteristics of The Diseased Mitral
Abstract Mitral valve tissue is an important part of human heart , mitral valve prolapse is the mitral valve (anterior , posterior lobe or both lobes ) in ventricular systole off into the left atrium ( left atrial side bulging ) , with or without mitral regurgitation mitral regurgitation can cause left ventricular dilatation and left ventricular dysfunction , in general , about 10-20 % of people have this phenomenon, but most people are asymptomatic itself is not much research significance and necessary, and mitral valve chordae rupture almost always lead to acute , often severe mitral regurgitation , or to acute exacerbation of chronic mitral regurgitation , so research two mitral valve chordae rupture properties for the detection of pathological etiology and clinical mitral valve repair surgery has a very important significance . rather difficult due to the complex biological mechanisms and physiological detection system itself we had to use circuit simulation quantitative analysis . The traditional circuit simulation system is generally a diode in series with a linear or non-linear resistance of such a simple model to simulate . This method is to simulate the characteristics of one-way flow of blood . But it ignores the important features such as the backflow of blood . Valvular physical characteristics.
This paper adopts the bench hydraulic control valve simulation experiment ends of Water Conservancy pressure changes , resulting in relatively accurate mitral valve characteristic curve.This paper describes the experimental paper first introduces some background information such as the current research and guidance for this experiment . Then for several changes throughout the experiment and the adjustment of the entire experimental setup are described and analyzed , the experimental results have also been preliminary processing , fluid properties will then be further processed in accordance with the results to obtain more accurate mitral characteristic curve.
The main significance of this experiment is to use hydraulic simulation of blood flow , and use real pig heart mitral experiment avoided the circuit model for the biological characteristics of the valve ignored , can more accurately measure the liquid through the mitral chordae rupture changes in pressure and flow valve , the mitral valve for simulation modeling and the whole left heart circulatory system plays an important role in guiding .
Key words： Mitral valve disease Chordal rupture Atrioventricular pressure Blood flow direction Mitral valve characteristic curve
目 錄
第一章 緒論 1
1.1 二尖瓣腱索斷裂的研究歷史及發(fā)展現(xiàn)狀 1
1.1.1 二尖瓣腱索斷裂研究的發(fā)展狀況 1
1.1.2 心血管建模仿真技術(shù)的現(xiàn)況 1
1.2 課題研究的背景、主要內(nèi)容及意義 2
1.2.1 課題研究的背景 2
1.2.2 課題的主要研究內(nèi)容及意義 4
1.3 小結(jié) 4
第二章 經(jīng)由二尖瓣的血液循環(huán)原理結(jié)構(gòu) 5
2.1左心血液循環(huán)過程 5
2.2 二尖瓣的模型 6
2.3 模擬左心環(huán)境的實驗裝置整體設(shè)計 6
2.4 小結(jié) 7
第三章 實驗裝置設(shè)計及實驗流程 8
3.1 實驗總體設(shè)計 8
3.2靜態(tài)實驗裝置搭建 8
3.3動態(tài)實驗裝置搭建 12
第四章 實驗步驟 16
4.1實驗準備及注意事項 16
4.1.1二尖瓣數(shù)據(jù)記錄 16
4.1.2二尖瓣解剖流程 16
4.1.3 二尖瓣安裝步驟 17
4.2 靜態(tài)實驗 18
4.2.1 靜態(tài)正向?qū)嶒炦^程 18
4.2.2 靜態(tài)返流實驗過程 19
4.3動態(tài)實驗 20
4.4 小結(jié)和實驗結(jié)果預(yù)測 21
第五章 實驗結(jié)果及分析 22
5.1 實驗設(shè)計 22
5.2 系統(tǒng)測試調(diào)試 22-..
